Presenting the new and improved dermamelan®, the benchmark medical depigmentation method used worldwide.

Mesoestetic®, a world leader in aesthetic and cosmetic medicine, has launched the upgraded dermamelan® formula, a topical depigmenting method medically applied to treat the appearance of dark spots. Skin hyperpigmentation is a growing global skin concern in all ethnicities and skin phototypes. It can have a negative impact on the patient’s quality of life, which is why mesoestetic® has spent over 30 years constantly pursuing innovation in the field of depigmentation. This has resulted in the mesoestetic® pharma group laboratory developing renowned depigmenting solutions, which has reinforced the company’s position of leadership in this field.

Dedicating over 5 years of research, mesoestetic® has launched this innovative upgraded formula, providing a more efficient depigmenting action while reducing the protocol time frames, making it even more effective and comfortable for the patient.

R&D has been key in this development, leading the laboratory to file two new patented components: a new molecule synthesised in-house and a complex of active ingredients.

What makes dermamelan® unique?

dermamelan® provides an all-round treatment method thanks to its dual mechanism of action that persists over time and helps prevent the appearance of pigmentation. The unique formula gradually encourages the skin renewal process, treating the appearance of existing dark spots while also promoting a gradual intensive corrective action on the reappearance of future skin discolouration. Additionally, it acts as a powerful anti-ageing treatment. The skin’s renewal process results in visibly increasing skin luminosity and minimises the appearance of wrinkles and expression lines.

• melaphenone® mesoestetic has designed, modelled and synthesised this synthesis molecule. Its molecular structure and 3D conformation provide a high specificity and reliability in visibly moderating and reducing the appearance of pigmentation.
• (SYN)pigmentarget® is an exclusive complex that is a unique combination of three selected active ingredients formulated at optimum concentrations, for a high-synergism response in the appearance of pigmentation.

The upgraded dermamelan® features two technologies that facilitate effective delivery and absorption of active ingredients towards the target areas: encapsulation by means of nanovesicles (to enhance the active ingredients’ absorption) and delivery via iontophoresis (a technique that creates penetration channels and improves the active ingredients’ efficacy).

Significant protocol improvements

• Treatment time (4 hours)
  New developments have allowed for a significant reduction in the method’s exposure time during the in-clinic phase, reducing it down to 4 hours total, regardless of phototype (as opposed to 8-12 hours previously). This breakthrough has been achieved as a result of the active ingredients being more powerful and the delivery technology.
• Total treatment time (4 months)
  In turn, the at-home protocol’s time frame has also been reduced thanks to the efficacy improvements made to the home care formula (previously it was 6 months).

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